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A study on the correlation between the motion and thickening fraction of diaphragmatic and TOFR of adductor pollicis

A study on the correlation between the motion and thickening fraction of diaphragmatic and TOFR of adductor pollicis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000033277
Enrollment
Unknown
Registered
2020-05-26
Start date
2020-05-31
Completion date
Unknown
Last updated
2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Residual muscle relaxation

Interventions

Gold Standard:TOF < 0.9
Index test:The&#32
and&#32
of&#32
(DIA,&#32
TF).

Sponsors

Department of Anesthesiology, Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Non cardiothoracic and upper abdominal surgery patients, 2. ASA I - II patients aged 25-65 years; 3. For the patients whose operation time is less than 3 hours, the bleeding volume is less than 5 ml / kg.

Exclusion criteria

Exclusion criteria: 1. Patients with cardiovascular diseases; 2. Patients with severe hepatorenal dysfunction; 3. Patients with neuromuscular diseases; 4. Patients with acute and chronic respiratory diseases and thoracic deformity; 5. Patients with chronic metabolic diseases; 6. Patients with pleural effusion or tumor affecting diaphragm function; 7. Patients with abnormal preoperative pulmonary function (FEV1 / FVC < 70%; FEV1 < 80% predicted value); 8. Patients who use drugs that may affect neuromuscular conduction before operation; 9. Patients with trauma operation in the monitoring site of muscle relaxation within 3 months; 10. Patients with skin infection and damage at the chest and abdominal wall ultrasonic examination site; 11. Patients without informed consent. 12. Pregnant women.

Design outcomes

Primary

MeasureTime frame
motion of diaphragmatic;thickening fraction of diaphragmatic;TOFr;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactLianhua Chen

Shanghai General Hospital

spinny8898@sina.com+86 13818945841

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026