Congenital hydronephrosis
Conditions
Interventions
Gold Standard:Clinical outcomes
Index test:Matrix 
remodeling 
protein-5 
(MXRA5) 
in 
exosomes
Sponsors
Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 0.1 Years
Inclusion criteria
Inclusion criteria: 1. Postnatal unilateral renal pelvis anteroposterior diameter(APD)>= 10mm; 2. Voluntarily participate in this study with the informed consent of the guardian of the child; 3. The parents of the child have good compliance, and can regularly check and receive follow-up visits.
Exclusion criteria
Exclusion criteria: (Participants who meet any of the following criteria will not be eligible to participate in the study): 1. Patients with diseases of endocrine and metabolic systems, liver and kidney diseases, blood system diseases and genetic diseases; 2. Children receiving hormone drug therapy;Bilateral hydronephrosis;Ureterovesical reflux; 3. Ureteral dilatation or abnormal lower urinary tract;Isolated kidney.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MXRA5 expression in Exosome;SEN, SPE, ACC, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| MXRA5 expression in urine supernatant; | — |
Countries
China
Contacts
Public ContactDapeng Jiang
Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine
Outcome results
None listed