Traumatic brain injury, sleep, cognitive impairment
Conditions
Interventions
experimental group:10 mg zolpidem tartrate tablets before bed
Control group:Starch flakes
Sponsors
Haining People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with a clear history of TBI were diagnosed by imaging examination; 2. TBI: Glasgow Coma Scale (GCS) score > 8, coma time <= 6 h; 3. Patients aged 18-70 years old, male and female unlimited; 4. After the patient's condition is stable, the patient and his family members have informed consent and voluntarily participate in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with previous history of TBI, cerebrovascular accident, intracranial space occupying lesions, epilepsy or other intracranial lesions; 2. Patients who have a history of mental illness, drug use or long-term alcohol abuse; 3. Patients with severe multiple injury and severe liver and kidney function injury; 4. Patients with previous history of diabetes, malignancies and other systemic diseases; 5. Patients who are manic or unable to cooperate with assessment due to other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Polysomnogram monitoring;PSQI;MoCA-B; | — |
Secondary
| Measure | Time frame |
|---|---|
| Growth hormone;Thyroxine; | — |
Countries
China
Contacts
Public ContactChen Weiliang
Haining People's Hospital
Outcome results
None listed