osteoporosis
Conditions
Interventions
APR group:symptomatic treatment
Control group:nil
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
55 Years to 89 Years
Inclusion criteria
Inclusion criteria: 1) age: 55~89 (postmenopausal female), 60~89 (male); 2) dual-energy X-ray bone mineral density examination of T < -2.5 or T < -1.5 with history of brittle fracture.
Exclusion criteria
Exclusion criteria: 1) patients had received intravenous zoledronic acid treatment (5mg migoda or 4mg zeitai); 2) allergic to zoledronic acid or bisphosphonates; 3) serum calcium ion < 1.10 mmol/L; 4) creatinine clearance rate < 35mL/min; 5) patients with malignant tumors; 6) severe cardiovascular, liver, endocrine, urinary and nervous system diseases; 7) combined mental illness; 8) patients who underwent internal fixation of lumbar vertebra and hip to affect the results of bone mineral density test; 9) refuse to participate in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMD (bone mineral density);temperature;pain;N-MID;TP1NP;ß-CTx;PTH;CT;Vit-D3;TNF-a;IL-6;IFN-?; | — |
Countries
China
Contacts
Public ContactJiang Wei
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed