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Clinical evaluation of coronally advanced flap with acellular dermal matrix graft or connective tissue graft in the treatment of gingival recessions with thin periodontal phenotype: a split-mouth randomized clinical trial

Clinical evaluation of coronally advanced flap with acellular dermal matrix graft or connective tissue graft in the treatment of gingival recessions with thin periodontal phenotype: a split-mouth randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033230
Enrollment
Unknown
Registered
2020-05-25
Start date
2020-06-01
Completion date
Unknown
Last updated
2020-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival recession

Interventions

Experimental group:Coronally advanced flap with acellular dermal matrix graft
Control group:coronally advanced flap with connective tissue graft

Sponsors

Peking University School and Hospital of Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years; 2. Patients willing to provide an informed consent and attend the study; 3. Systemically healthy and no contraindications for periodontal surgery; 4. Presence of localized bilateral Miller class I or II adjacent gingival recessions >=3mm with thin periodontal phenotype in the maxillary or mandibular arches without any clinical sign of active/chronic periodontal disease; 5. Having full-mouth plaque score and full-mouth bleeding score < 15%; 6. No history of surgical intervention in the relevant areas.

Exclusion criteria

Exclusion criteria: 1. Habitual tobacco smoking and/or chewing; 2. Habitual alcohol consumption; 3. Pregnancy or lactating women; 4. Participants having crowns or restorations involving the CEJ or those with nonidentifiable CEJ; 5. Individuals using medications that can interfere with healing and allergic to penicillin.

Design outcomes

Primary

MeasureTime frame
Recession depth;Mean root coverage;Complete root coverage;keratinized tissue width;Root coverage aesthetic score;Change of profile;Patient satisfaction;VAS scale to aesthetic;

Secondary

MeasureTime frame
Recession width;Color change;

Contacts

Public ContactYalin Zhan

Peking University School and Hospital of Stomatology

zhanyalin2014@126.com+86 010-53295162

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026