Carotid atherosclerosis
Conditions
Interventions
Sponsors
Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. The patients with carotid atherosclerotic plaques were diagnosed by color Doppler ultrasound; 2. hsCRP >= 2 mg/L; 3. The syndrome differentiation of traditional Chinese medicine is mainly the patients with stasis heat and internal depression; 4. Patients between 40 and 70 years old, regardless of gender; 5. Patients who can take medicine for a long time; 6. Patients who have informed consent and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with acute stage of cardiovascular and cerebrovascular diseases; 2. Patients with previous history of cerebral hemorrhage; 3. Patients with other active ulcers and bleeding tendency who take anticoagulants (such as warfarin) for a long time; 4. Patients with serious arrhythmia, atrial fibrillation and heart failure; 5. Patients with severe liver, kidney, hematopoietic system, endocrine system, respiratory system, hypertension, infectious and non infectious inflammation, immune related and other primary diseases, whose liver function is more than 1.5 times higher than the upper limit of the normal value, and whose Cr is higher than the normal value; 6. Patients who are using antidotal and blood activating drugs, antibiotics, hormones, immunosuppressants, IL-1 ß monoclonal antibodies and other drugs that affect hsCRP; 7. Patients with gastrointestinal dysfunction, diarrhea and abdominal distention; 8. Pregnant or lactating women, women with a recent pregnancy plan; 9. Patients with allergic constitution; 10. Any other life-threatening or serious disease that cannot be treated for 3 months and thus affects the evaluation results; 11. Other diseases or psychosis that may limit efficacy evaluation or patient follow-up in the opinion of researchers; 12. Patients who have participated in clinical trials of other drugs in the past 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High sensitive C-reactive protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin-6;Four items of blood lipid;Fasting blood glucose; | — |
Countries
China
Contacts
Public ContactWu Shengxian
Dongzhimen Hospital of Beijing University of traditional Chinese Medicine
Outcome results
None listed