Late Complication of Chronic Radiation Proctitis
Conditions
Interventions
Case series:PE-Bacon surgery
Sponsors
Sixth Affiliated Hospital, Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-70 years; 2. Patients with ECoG physical condition score of 0-2; 3. Patients with previous pathological diagnosis of pelvic tumors (Gynecology, prostate, urinary system); 4. Patients with a history of pelvic radiotherapy, at least 6 months from the end of the last radiotherapy; 5. Patients without recurrence or metastasis of primary tumor; 6. The late complications of CRP patients, such as deep rectal ulcer (VRS score >=3), rectal sigmoid colon stenosis, obstruction, chronic perforation, rectal necrosis, rectovaginal fistula, intractable anal pain caused by rectal lesions, intractable rectal bleeding which is still difficult to be relieved by stoma operation, and patients who need sigmoid colorectal resection; 7. Patients who can tolerate general anesthesia; 8. The subjects and their families are able to understand the study plan, willing to participate and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with acute intestinal obstruction, acute intestinal perforation and intestinal hemorrhage who need emergency operation; 2. Patients with severe pelvic adhesion and frozen pelvis; 3. Patients with unstable primary tumor or tumor in other parts; 4. Patients who need to undergo combined organ resection; 5. Patients with a history of sigmoidostomy; 6. ASA level IV to V; 7. Patients with serious mental illness; 8. Pregnant or lactating women; 9. Patients with serious cardiovascular disease, uncontrollable infection, or other uncontrollable combined diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative anastomotic leakage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative anastomotic stenosis;Incidence of postoperative anastomotic hemorrhage;The anus function after stoma closure; | — |
Countries
China
Contacts
Public ContactTenghui Ma
Sixth Affiliated Hospital, Sun Yat-Sen University
Outcome results
None listed