Acute respiratory failure
Conditions
Interventions
NIV group: Noninvasive ventilation
HFNC group:high nasal flow oxygen therapy
Sponsors
Changshu Hospital Affiliated to Changshu First People's Hospital Affiliated to Suzhou University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years or older and less than 80 years old; 2. Meet the following conditions: (1) Respiratory rate > 25 times / min; (2) Under the condition of 10 L / min oxygen inhalation with air bag mask and 15 minutes observation, PaO2 / FiO2 of patients was = 7.30. 3. Patients willing to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe asthma or acute exacerbation of COPD; 2. Patients with severe granulocytopenia ( 10 µ g / kg / min, noradrenaline > 0.1ug/kg/min; 4. Patients with Glasgow Coma Scale score <=12; 5. Noninvasive ventilation contraindications: weak spontaneous respiration; aspiration; combined with other organ failure; facial trauma; upper abdominal surgery or post-traumatic; deformity; patient uncooperative; 6. Patients who need emergency intubation, refuse intubation and refuse to participate in the experiment; 7. Patients who have been included in this study are readmitted, or are participating in other studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intubation rate within 28 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory function;Hemodynamic index;Mortality within 28 days;Organ function within 28 days;The length of ICU stay;The length of hospital stay;complications; | — |
Countries
China
Contacts
Public ContactYufeng Feng
Changshu First People's Hospital Affiliated to Suzhou University
Outcome results
None listed