Skip to content

A prospective cohort study of the correlation between inflammation indicators and the clinical efficacy and safety of rivaroxaban

The effect of serum IL-6 level in elderly patients on the clinical efficacy and safety of rivaroxaban

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000033144
Enrollment
Unknown
Registered
2020-05-22
Start date
2020-07-01
Completion date
Unknown
Last updated
2020-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thromboembolic disease

Interventions

inflammation group:N/A
no inflammation group:N/A

Sponsors

The Fifth People's Hospital of Shanghai
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 110 Years

Inclusion criteria

Inclusion criteria: 1. Patients over 65 years old, diagnosed with atrial fibrillation, with or without infection, are not limited to men and women. 2. An informed consent was signed before blood samples were collected.

Exclusion criteria

Exclusion criteria: 1. History of drug allergy, patients receiving immunosuppressive drugs or low molecular weight heparin anticoagulant drugs, taking drugs that affect blood coagulation, lactose allergy, bleeding tendency, blood disease platelet count > 400 x 10^9 / L or 169 or < 100 g / L, history of peptic ulcer; 2. Severe dysfunction or failure of multiple organs such as heart, liver and kidney; 3. Malignant tumors, epilepsy and other nervous system diseases; 4. Anticoagulant drugs have been used together, including antiplatelet drugs, heparin, low molecular weight heparin, warfarin, non-vitamin K-dependent oral anticoagulant drugs, such as dabigatran, apixaban, etc.; 3. Anticoagulant drugs, such as heparin, low-molecular-weight heparin, fondaparinux sodium, warfarin, etc., were used 2 weeks before blood collection.

Design outcomes

Primary

MeasureTime frame
Inhibition of FXa;IL-6;

Countries

China

Contacts

Public ContactYan Yu

The Fifth People's Hospital of Shanghai

yuyanbooket@126.com+86 021-24289464

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026