Birth Defects
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Pregnant women need to be delivered in the research unit; 2. The age of the pregnant woman during the expected delivery period >=35 years old, and the time of the first consultation <=13 + 6 weeks; 3. Willing to accept 2-3 postpartum follow-ups; 4. Pregnant women have the ability to read, understand and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant women have malignant tumor diseases, cardiovascular diseases and other diseases that may affect the research results; 2. Known severe fetal malformation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serological screening in early pregnancy;Serological screening in mid-pregnancy;Prenatal diagnosis;Pregnancy outcomes;Fetal or neonatal outcomes; | — |
Countries
China
Contacts
Women's Hospital, Zhejiang University