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Effect of hydromorphone on analgesia and inflammatory factors in patients with hemorrhoid surgery

Effect of hydromorphone on analgesia and inflammatory factors in patients with hemorrhoid surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033121
Enrollment
Unknown
Registered
2020-05-21
Start date
2020-06-10
Completion date
Unknown
Last updated
2020-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Management

Interventions

Group 1:Give normal saline
Group 2:Hydromorphone was diluted to 5mL intravenous slowly 10min before anesthesia

Sponsors

Shiyan People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The patients who choose to have the procedure of prolapse and hemorrhoids; 2. Patients aged 18-65 years; 3. Patients with ASA grade I-II had no serious cardiopulmonary disease, normal liver and kidney function, and no mental system disease before operation; 4. Patients with body mass index (BMI) of 18-28kg / m2; 5. All patients sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients without accompanying or guardian; 2. Uncontrolled patients with severe hypertension, serious arrhythmia and unstable angina; 3. Patients with liver dysfunction (above child Pugh Level C); 4. Patients with severe renal dysfunction (CR clearance < 30 ml / min); 5. Patients with abnormal hearing and vision unable to communicate; 6. Patients with neuromuscular diseases; 7. Patients who are allergic to drugs or who are allergic to drugs or have other contraindications; 8. Patients who have participated in additional drug clinical trials in the past 30 days.

Design outcomes

Primary

MeasureTime frame
VAS pain score;haemodynamics;inflammatory factor;stress reaction;

Countries

China

Contacts

Public ContactYun Xiao

Postgraduate Training Base of Hubei Medical College of Jinzhou Medical University

xiaoyun5598@163.com+86 15907287568

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026