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An RCT test of the efficacy and survival analysis of urokinase at room temperature after infusion of DD

An RCT test of the efficacy and survival analysis of urokinase at room temperature after infusion of DD

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033071
Enrollment
Unknown
Registered
2020-05-19
Start date
2020-05-19
Completion date
Unknown
Last updated
2020-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney transplantation

Interventions

experimental group:Urokinase with HCA infusion
Control group:HCA perfusion

Sponsors

The Second Affiliated Hospital of Nanhua University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Supplier: Aged >= 16 years or kidney volume up to standard; The recipient comes from DD donor or expanded criteria donor (ECD) donor; Two kidneys of the donor were transplanted to two different recipients; Normal renal function; HIV negative; There was no malignant tumor. 2. Recipient: Before operation, human leukocyte antigen (HLA) and other related matching tests were completed; The routine examination was completed on the day of operation; There was no contraindication for renal transplantation; Preoperative panel reactive antibody (PRA) was less than 10%.

Exclusion criteria

Exclusion criteria: 1. Donor: ? 2 arteries or veins; 2. Recipient: died within one week after transplantation (only one week after surgery can determine whether the patient developed DGF); those who have two or more transplants.

Design outcomes

Primary

MeasureTime frame
DGF incidence;Serum creatinine;

Secondary

MeasureTime frame
Time to urinate;Urine output;

Countries

China

Contacts

Public ContactLuo Zhigang

The Second Affiliated Hospital of Nanhua University

706885399@qq.com+86 13907342350

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026