Skip to content

Effect of taking simethicone at different time points on intestinal preparation quality and adenoma detection rate: a prospective randomised controlled trial

Effect of taking simethicone at different time points on intestinal preparation quality and adenoma detection rate: a prospective randomised controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000033058
Enrollment
Unknown
Registered
2020-05-19
Start date
2020-06-01
Completion date
Unknown
Last updated
2020-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Adenomas

Interventions

A group:At 19:00 of the day before colonoscopy, 1000ml of polyethylene glycol + 200mg of dimethylsilicone oil were taken, and another 1000ml of polyethylene glycol was taken 4-6h before colonoscopy.
B group:1000 ml of polyethylene glycol was taken at 19:00 of the day before colonoscopy, and another 1000 ml of polyethylene glycol + 200 mg of silicone oil were taken 4-6 hours before colonoscopy.

Sponsors

Department of Gastroenterology, Shenzhen People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-80 years, male and female unlimited; 2. Subjects willing to receive colonoscopy; 3. Subjects willing to sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Subjects allergic to silicone oil; 2. Patients with colectomy; 3. Patients with familial polyposis; 4. Patients with P-J syndrome; 5. Pregnant objects; 6. IBD ; 7. Patients with colon cancer.

Design outcomes

Primary

MeasureTime frame
Boston bowel preparation scale BBPS;Bubble scale BS;Adenoma detection rate, ADR;

Secondary

MeasureTime frame
polyp detection rate, PDA;Cecal intubation rate, CIT;Withdrawal time, WT;SSP/SSA detection rate;Advent events;

Countries

China

Contacts

Public ContactLisheng Wang

Shenzhen People's Hospital

wangls168@163.coml+86 13714725662

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026