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Efficacy of Early Prone Positioning in Non-Mechanical Ventilation novel coronavirus pneumonia (COVID-19) Patients with Severe Hypoxia- a single-center prospective cohort study

Efficacy of Early Prone Positioning in newly admitted novel coronavirus pneumonia (COVID-19) patients with severe hypoxia: a single-center prospective cohort study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000033053
Enrollment
Unknown
Registered
2020-05-19
Start date
2020-02-01
Completion date
Unknown
Last updated
2020-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel Coronavirus Pneumonia (COVID-19)

Interventions

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The COVID-19 patient is diagnosis by nucleic acid detection, who has obvious clinical features of viral pneumonia; 2. The COVID-19 patient with severe hypoxia requires the use of oxygen storage masks, and whose pulse oxygen saturation can be maintained at about 90%; 3. The COVID-19 patient has the ability to move independently with age range from 18-80 years old; 4. Informed consent form of COVID-19 patient is signed by myself and agent.

Exclusion criteria

Exclusion criteria: 1. conditions that cannot be tolerated in prone positioning or prone positioning can easily cause injury, such as having neurological or mental problems, and inability to move autonomously; 2. Spinal cord injury or fracture (vertebral body fracture, pelvic fracture, multiple fractures, flail chest, etc.) that has not yet stabilized;Increased intracranial pressure without relief; Severe burned; Recently abdominal surgery; Abdominal hypertension; Head and face injuries; Tracheotomy; Maternal; Severe chronic lung disease; 3. Unstable hemodynamic status or other organ failure should be treated in ICU; 4. Patients with no hope of survival and only hospice care were clinically predicted, or those who were in a deep coma and did not respond to the supportive treatment measures within three hours after admission.

Design outcomes

Primary

MeasureTime frame
pulse oxygen saturation;respiratory rate;ROX index;

Secondary

MeasureTime frame
CT Scan-Chest;outcome;

Countries

China

Contacts

Public ContactZang Xuefeng

Beijing Shijitan Hospital, Capital Medical University

zangxuefeng@126.com+86 15201231027

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026