Skip to content

Endoscopic Stricturotomy for Refractory Anastomotic Strictures After Esophagectomy: a Pilot Clinical Study

Endoscopic Stricturotomy for Refractory Anastomotic Strictures After Esophagectomy: a Prospective, Sigle Arm Clinical Study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032997
Enrollment
Unknown
Registered
2020-05-17
Start date
2020-05-31
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal anastomosis strictures

Interventions

endoscopic stricturotomy group:endoscopic stricturotomy

Sponsors

The Second Affilated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients older than 18 years and younger than 75 years, regardless of gender 2. Patients who meet the criteria of persistent anastomotic stenosis after esophagectomy; Diagnostic criteria of intractable stenosis: Patients with dysphagia received EBD for more than 3 times continuously (4 weeks) and the symptoms recurred or did not relieve. 3. Patients who are willing to participate in the trial and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with distant metastasis or survival less than 6 months; 2. Patients undergoing radiotherapy and chemotherapy; 3. Patients with reflux esophagitis who refused PPI treatment; 4. Pregnant or breast preserved women; 5. Long term hormone users / patients with anticoagulants or antiplatelet drugs; 6. Patients with severe bleeding tendency or thrombocytopenia; 7. Patients with severe cardiopulmonary disease who can not receive endoscopic surgery; 8. Patients who do not sign informed consent.

Design outcomes

Primary

MeasureTime frame
Duration of dysphagia degree = I after endoscopic therapy;

Secondary

MeasureTime frame
Success rate;Recurrent rate;Sessions of ES;Intervals between of endoscopic therapies;Procedure time;Hospital stays;Hospitalization ost;Complications;

Countries

China

Contacts

Public ContactXiao Ma

Second Affilated Hospital of Harbin Medical University

mx_1983@yeah.net+86 13674646034

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026