Malignant central airway stenosis
Conditions
Interventions
Experimental group:Airway stenting
control group:No airway stent
Sponsors
The First Affiliated Hospital of Suzhou University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The subjects were over 18 years old, male or female without pregnancy; 2. The subjects / legal authorized representatives understand the purpose and procedure of the test and sign the informed consent voluntarily; 3. The subjects must be in accordance with the diagnosis of central airway stenosis caused by primary or secondary lung tumor in the late stage, and more than 50% of patients with stenosis degree confirmed by chest CT examination; 4. Female subjects are not in lactation period at the time of screening visit, and there is no lactation or pregnancy plan for up to 1 year after the initial operation; 5. Subjects have not participated in other clinical trials in the first three months and agree not to participate in other clinical trials before reaching the end point of this trial; 6. Subjects who were unable or refused to receive surgical treatment.
Exclusion criteria
Exclusion criteria: 1. The subjects could not cooperate with the tracheoscopy or did not sign the informed consent of the study; 2. Patients with serious arrhythmia, acute myocardial ischemia, uncontrolled hypertension crisis; 3. Patients with coagulation dysfunction (PT time > 2 times of the upper limit of normal or PLT < 50x10^9/L); 4. Patients with severe organ dysfunction (including shock, severe hepatorenal dysfunction, upper gastrointestinal hemorrhage, DIC, hemoptysis, etc.); 5. Patients who are allergic to narcotic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective time of airway stent; | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of airway stents on quality of life and survival time; | — |
Countries
China
Contacts
Public ContactJunhong Jiang
The First Affiliated Hospital of Suzhou University
Outcome results
None listed