Effects of dexmedetomidine on analgesia ED50 after ropivacaine for ultrasound-guided transversal abdominal muscle plane block: a randomized controlled double-blind prospective study

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000032991

Enrollment

Unknown

Registered

2020-05-17

Start date

2020-05-15

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic cholecystectomy

Interventions

The control group:Ropivacaine

The experimental group:Ropivacaine and dexmedetomidine

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-65 years; 2. Patients with ASA grade I-II; 3. Patients with selective laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: 1. Patients with abnormal coagulation before operation; 2. Patients with skin infection and damage at the puncture site; 3. Patients with BMI 30 kg / m2; 4. Patients with bradycardia, atrioventricular block and cardiac insufficiency; 5. Patients who are allergic to ropivacaine and dexmedetomidine; 6. Patients with serious damage to liver and kidney function; 7. Patients with a history of chronic pain.

Design outcomes

Primary

Measure	Time frame
VAS score;	—

Secondary

Measure	Time frame
Anesthetic dosage;QoR40 score;Postoperative adverse reaction;	—

Countries

China

Contacts

Public ContactFangjun Wang

North Sichuan Medical College

wfjlxy006@126.com+86 13458253172

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026