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Development of Biomarkers for Biliary Atresia and Establishment of Artificial Intelligence Diagnostic Model

Development of Biomarkers for Biliary Atresia and Establishment of Artificial Intelligence Diagnostic Model

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000032983
Enrollment
Unknown
Registered
2020-05-17
Start date
2020-08-01
Completion date
Unknown
Last updated
2020-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary atresia

Interventions

Sponsors

Children's Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Children with obstructive jaundice to be operated on; 2. Children with age = 28 weeks at birth are not limited to men and women; 4. Children with a body weight >= 1kg were enrolled.

Exclusion criteria

Exclusion criteria: 1. Children with known immune deficiency; 2. The children with hemolytic jaundice were 85.5 µ mol / L (5mg / dl) or 119.7 µ mol / L (7Mg / dl) in 4-8 weeks of life, 3. The mother of the children suffered from human immunodeficiency disease, HBsAg positive or hepatitis C virus positive; 4. Children with other infections (such as herpes simplex virus, Toxoplasma gondii, etc.); 5. Children with other systemic diseases.

Design outcomes

Primary

MeasureTime frame
MMP7;MMP7;bile acid profile;bile acid profile;SEN, SPE, ACC, AUC of ROC;IL33;IL33;

Countries

China

Contacts

Public ContactShan Zheng

Children's Hospital of Fudan University

szheng@shmu.edu.cn+86 15900898826

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026