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Characteristics and mechanisms of sleep disorders and cognitive impairments in patients with myotonic dystrophy 1

Characteristics and mechanisms of sleep disorders and cognitive impairments in patients with myotonic dystrophy 1

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000032978
Enrollment
Unknown
Registered
2020-05-17
Start date
2020-06-01
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myotonic dystrophy 1

Interventions

DM1:Nil

Sponsors

Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: The subjects should meet the following criteria: 1. Signed informed consent form with date. 2. Promise to abide by the research procedure and cooperate with the implementation of the whole process research. 3. Aged 20-80 years, regardless of gender. 4. Patients or healthy people who have been genetically verified as DM1

Exclusion criteria

Exclusion criteria: Subjects who meet any of the following criteria will be excluded from this study: 1. To install a specific device, such as a pacemaker; 2. There are other diseases that affect myasthenia gravis, such as myositis, myasthenia gravis, peripheral neuropathy, etc.; 3. There are other conditions that affect sleep, such as mental factors; 4. There are concomitant diseases that seriously affect health, such as tumors, severe abnormalities of liver and kidney function, and so on; 5. At the same time, those who participated in other clinical trials related to / not related to this clinical trial; 6. Unable to complete the questionnaire evaluator independently.

Design outcomes

Primary

MeasureTime frame
PSQI;ESS;RBD-SQ;RLS-SQ;AVLT;CFT;Trail Making A/B;SCWT;Word similarity test;Digit span test;Boston naming;Brain MRI scan;

Secondary

MeasureTime frame
PSG;TCS;Pulmonary function test;HAMA;HAMD;MMSE;

Countries

China

Contacts

Public ContactHai-Yan Zhou

Ruijin Hospital, Shanghai Jiaotong University School of Medicine

zhaiyan.com@163.com+86 13816607873

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026