Dental implants
Conditions
Interventions
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Subjects who voluntarily participated in the experiment and signed the informed consent; 2. Patients aged 18-75 years old, regardless of gender; 3. Subjects with dentition defect or missing dentition who need to be implanted with implants (each patient has at most 3 missing parts of dentition, and the number of implants used is not more than 2). Those who meet the above indications and have no systemic disease can bear the implant operation; 4. Subjects with good healing of alveolar fossa in the edentulous area or more than 3 months after tooth extraction; 5. Subjects with enough bone height and width in the edentulous area for implant implantation; 6. Healthy subjects with sufficient thickness and width of the implant area; 7. Subjects with no obvious inflammation or lesion of oral mucosa and soft tissue; 8. Subjects who are able to communicate well with the researchers and comply with the test requirements. Those who do not meet any of the above inclusion criteria shall not be selected.
Exclusion criteria
Exclusion criteria: 1. There are abnormal occlusal relationship or bad occlusal habits around the edentulous area, which may lead to implant failure due to trauma absorption of bone tissue around the implant; local alveolar bone has pathological changes; oral mucosal lesions; serious soft tissue lesions and serious periodontal diseases in the edentulous area; limited mouth opening; bone mass and bone density in the edentulous area are not ideal and difficult to change; 2. Patients with acute or severe infection and leukocyte count > 10 x 10^9 / L; 3. Pregnant and lactating women; 4. Patients taking special drugs for a long time, such as hormone, anticoagulant, diphosphate, etc.; 5. Patients with poor general and nutritional status who can't tolerate implant surgery; 6. Patients with history of heart or arteriosclerosis who can't tolerate implant surgery; 7. Patients with blood system diseases and uncontrolled cardiovascular diseases (hypertension [systolic pressure > 150mmhg, diastolic pressure > 90mmHg], coronary heart disease, congenital heart disease, etc.); 8. Systemic or local bone diseases are considered as contraindications of implant repair, such as bone tuberculosis, osteitis, bone tumor, etc; 9. Patients with systemic immune diseases; 10. Patients with severe epilepsy or mental illness or mental disorder; 11. The fasting blood glucose was more than 7.0mmol/l in the patients without diabetes control; 12. Patients with radiotherapy history of head and neck or chemotherapy history within 5 years; 13. Patients with metal material allergy; 14. Patients whose clotting time is more than twice of the normal range; 15. Subjects who participated in other clinical trials within one month at the time of selection; 16. Subjects who are not suitable for this clinical trial due to other reasons. If any of the above exclusion criteria is met, it shall be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ratio of dental implantation and; | — |
Secondary
| Measure | Time frame |
|---|---|
| Implant stability;Postoperative healing;Bone mass around implant after operation;Aesthetic effect after restoration; | — |
Countries
China
Contacts
Public ContactDerong Zou
Shanghai Sixth People's Hospital
Outcome results
None listed