Depression
Conditions
Interventions
Sponsors
The First Affiliated Hospital, College of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Research Group: 1. Patients who sign written informed consent and are willing to participate in the trial and receive treatment; 2. Patients aged 18-60 years; 3. The diagnosis standard of dsm-5 depression attack was met; 4. Patients with right handedness; Control group: 1. Subjects who sign written informed consent and are willing to participate in the trial and receive treatment; 2. Subjects aged 18-45 years; 3. Healthy subjects; 4. Right handed subjects.
Exclusion criteria
Exclusion criteria: 1. Pregnant, lactating or planned pregnancy; 2. Patients with previous history of epilepsy; 3. Patients with serious nervous, heart, liver, kidney, endocrine, blood system and other physical diseases; 4. Patients with metal objects in the body; 5. Patients with organic mental disorders and mental retardation; 6. Patients with alcohol dependence; 7. Patients with drug dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BDNF;ERK;ELK;Hypocretin;CREB;MINI International Neuropsychiatric Interview;Hamilton Depression Scale, HAMD;Beck Scale for Suicide Ideation-Chinese Version, BSI-CV;cognitive function;the brain gray matter density;fMRI; | — |
Countries
China
Contacts
Public ContactHuang Manli
The First Affiliated Hospital of Zhejiang University Medical College
Outcome results
None listed