Lumbar disc herniation
Conditions
Interventions
Minimally invasive group:Endoscopic discectomy through foramen approach
open surgery group:Posterior lumbar discectomy and internal fixation
Sponsors
East China Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. In patients with low back pain and lower extremity radiation pain, the skin sensation and muscle strength of one leg decreased, and the knee tendon reflex or / and Achilles tendon reflex decreased; 2. Imaging examination showed that the imaging manifestations of the patients with lumbar disc herniation and compression nerve were consistent with the clinical symptoms and signs, especially whether the left and right sides of the clinical manifestations were consistent with the left and right sides of the imaging; 3. Patients who have undergone lumbar open surgery or lumbar foramen surgery in our hospital; 4. Patients with VAS score of 4-6.
Exclusion criteria
Exclusion criteria: 1. Imaging examination showed that patients with lumbar spondylolisthesis, spinal tumor, spinal tuberculosis, severe osteoporosis and lumbar stenosis had undergone open surgery; 2. Patients with other contraindications to surgery, such as pregnant or lactating women, psychopaths, with cardiovascular, cerebrovascular, liver, kidney, hematopoietic system diseases, who can not tolerate surgery after consultation and evaluation by a specialist. 3. Patients with severe nerve compression symptoms such as obvious lower extremity muscle atrophy and cauda equina syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cross-sectional area of multifidus;fatty infiltration rate of multifidus;cross-sectional area of musculus erectus;fatty infiltration rate of musculus erectus; | — |
Countries
China
Contacts
Public ContactQi Han
East China Hospital Affiliated to Fudan University
Outcome results
None listed