Effects of depth of anesthesia monitored by index of consciousness on patients undergoing laparoscopic radical resection of colorectal cancer: a randomized controlled trial.

Effects of depth of anesthesia monitored by index of consciousness on patients undergoing laparoscopic radical resection of colorectal cancer

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000032867

Enrollment

Unknown

Registered

2020-05-14

Start date

2016-01-15

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Group A:IoC2 25-35

Group B:IoC2 35-45

Group C:IoC2 45-55

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged over 18 years; 2. American Society of Anesthesiologists (ASA) class II or III; 3. Scheduled to undergo a laparoscopic radical resection for colorectal cancer.

Exclusion criteria

Exclusion criteria: 1. Presented with heart, liver, kidney and lung dysfunction; 2. Without a history of propofol, remifentanil or other drug allergy; 3. With a history of alcohol abuse; 4. Weighed more than 20% of the average weight; 5. With endocrine or immunological diseases or undergoing chemoradiation or immunotherapy; 6. Using drugs that impacted the nervous system within 7 days before the surgery; 7. With mental illness; 8. With history of other serious diseases.

Design outcomes

Primary

Measure	Time frame
dosage of remifentanil;IoC1;IoC2;	—

Secondary

Measure	Time frame
blood pressure;heart rate;blood oxygen concentration;patients’ awakening time;	—

Countries

China

Contacts

Public ContactKang Zhenming

Department of Anesthesiology, Quanzhou First Hospital Affliated to Fujian Medical University

kangzhenming1@sina.com+86 15160768688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026