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A prospective study of roxadustat in reducing delayed graft function and acute rejection after renal transplantation

A prospective study of roxadustat in reducing delayed graft function and acute rejection after renal transplantation

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032858
Enrollment
Unknown
Registered
2020-05-13
Start date
2020-07-06
Completion date
Unknown
Last updated
2020-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

delayed graft function after kidney transplantation

Interventions

experimental group:Roxadustat and conventional treatment
control group:conventional treatment

Sponsors

The Third Affiliated Hospital,Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Recipients aged 18-70 years; 2. Patients with indications for renal transplantation; 3. Patients without contraindications; 4. Patients with first kidney transplantation; 5. Cadaveric kidney transplantation; 6. Patients who sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Children or living donors; 2. Patients with absolute contraindications to renal transplantation; 3. Patients with combined multiple organ transplantation; 4. Patients who are not prescribed in the scope of combined medication, especially those who are combined with drugs that have a greater impact on the test results and affect the judgment of effectiveness and safety; 5. Patients participating in other clinical trials; 6. Patients with previous history of other organ transplantation; 7. Other situations that the researchers think are not suitable for inclusion.

Design outcomes

Primary

MeasureTime frame
The incidence of delayed graft function, DGF;The incidence of acute rejection, AR;

Secondary

MeasureTime frame
hemoglobin;Urine volume;severe infectious rates;

Countries

China

Contacts

Public ContactQiquan Sun

The Third Affiliated Hospital, Sun Yat-Sen University

sunqiq@mail.sysu.edu.cn+86 18922103587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026