Efficacy and safety of remimazolam tosilate in procedural sedation during induction of anesthesia: a multicenter, randomized, single blind, positive control study

Efficacy and safety of remimazolam tosilate in procedural sedation during induction of anesthesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000032846

Enrollment

Unknown

Registered

2020-05-13

Start date

2020-06-01

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia

Interventions

Experimental group:remimazolam tosilate

control group:propofol

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. The operation time of patients with selective general anesthesia was more than 30 minutes; 2. Patients older than 18 and younger than 65 years; 3. American Society of anesthesiologists (ASA) grade I-II; 4. Patients without chronic liver and kidney dysfunction; 5. Patients who have not taken psychoactive drugs recently; 6. The subjects or their families signed the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: 1. Patients whose operation time is less than 30 minutes; 2. Patients not undergoing general anesthesia; 3. Patients who are allergic to benzodiazepines; 4. Patients with myasthenia gravis; 5. Patients with schizophrenia and severe depression; 6. Patients with obesity, snoring or body mass index (BMI) >=35kg/m2.

Design outcomes

Primary

Measure	Time frame
Vital signs;BIS;Sedation time;	—

Countries

China

Contacts

Public ContactZeyu Zhao

Sichuan Bayi Rehabilitation Center (Sichuan Rehabilitation Hospital)

gyzhaozy@163.com+86 18011310198

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026