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Establishment of screening method for pediatric glioma neoantigen and its application in the development of nasal vaccines for mRNA tumors

Establishment of screening method for pediatric glioma neoantigen and its application in the development of nasal vaccines for mRNA tumors

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000032822
Enrollment
Unknown
Registered
2020-05-12
Start date
2020-05-18
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric glioma

Interventions

Case series:Nil

Sponsors

Guangzhou Women and Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 16 Years

Inclusion criteria

Inclusion criteria: 1. Children with brain tumor requiring surgical treatment; 2. Patients who have no alternative therapy other than surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with alternative therapy other than surgery; 2. Patients who refuse to participate.

Design outcomes

Primary

MeasureTime frame
Tumor tissue WES + mRNA seq;Tumor tissue Ribo-LR LongRNA-seq;Paratumor tissue WES + mRNA seq;Paratumor tissue Ribo-LR LongRNA-seq;blood WES + mRNA seq;blood Ribo-LR LongRNA-seq;

Countries

China

Contacts

Public ContactLibilian

Guangzhou Women and Children Medical Center

13570226780@126.com+86 13570226780

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026