Stable Coronary Heart Disease
Conditions
Interventions
Control group:Placebo
Sponsors
Xiyuan Hospital of Chinese Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Results of coronary angiography or spiral CT: coronary stenosis >= 50%, or clear history of myocardial infarction, or stable condition more than one month after ACS treatment (PCI, CABG); 2. Patients with LVEF >= 40%; 3. Patients with angina I-II (CCS grade); 4. Patients with Qi deficiency and blood stasis syndrome; 5. Patients aged 18 to 75 years; 6. The patients who are in line with the risk stratification of coronary heart disease and have low risk of cardiac rehabilitation can be rehabilitated by exercise cardio pulmonary; 7. Patients willing to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with acute myocardial infarction, unstable angina, or within one month after PCI or CABG; 2. Patients with absolute and relative contraindications for cardiopulmonary exercise test; 3. Patients who took Zhenyuan capsule in the last month or who participated in other clinical trials in the last month; 4. In the patients with renal insufficiency, serum creatinine was more than 2.5mg/dl in men and more than 2.0mg/dl in women; 5. Patients with obvious liver disease or ALT and AST were 3 times higher than the upper limit of normal; 6. New York Heart Function (NYHA) grade IV, or patients with recurrent malignant arrhythmias; 7. Patients with chronic obstructive pulmonary disease or even respiratory failure, or patients with pulmonary infection; 8. Patients with diabetes mellitus whose blood glucose >=13.7mmol/l or HbA1c was >= 9.5%; 9. Pregnant or preparing pregnant women and lactating women; 10. Patients with acute cerebrovascular disease; malignant tumor or patients with life expectancy less than 1 year; patients with severe hematopoietic system disease; patients with severe mental disease; 11. Patients who are allergic to known components of the study drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak Oxygen Uptake(Peak VO2)(L/min); | — |
Countries
China
Contacts
Public ContactWang Chenglong
Graduate School of Chinese Academy of Traditional Chinese Medicine
Outcome results
None listed