Acute Coronary Syndrome
Conditions
Interventions
Group 1:oral ticagrelor beilinda 90mg
Group 2:oral ticagrelor meiluolin 90mg
Group 3:oral ticagrelor meiluolin 60mg
Group 4:oral ticagrelor meiluolin 45mg
Sponsors
Tangshan Worker Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged ?18 years; 2. Persons with a clinical diagnosis of acute coronary syndrome (established by the cardiovascular Branch of the Chinese Medical Association). 3. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Persons who are allergic to aspirin, clopidogrel, or ticagrelor; 2. Persons with contraindications to antithrombotic and anticoagulation; 3. Persons taking oral anticoagulants; 4. Persons planning to receive coronary-artery bypass grafting (CABG) within 6 months; 5. Persons with renal insufficiency requiring dialysis; 6. Persons with moderate or severe liver impairment; 7. Platelet count < 100 x 10^9/L; 8. Hemoglobin < 10 g/dL; 9. Persons receiving thrombolytic therapy; 10. Persons requiring surgical bypass; 11. Pregnancy or breast-feeding; 12. Serious concomitant illness associated with a life expectancy of less than 1 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| platelet aggregation rate (PAR); | — |
Secondary
| Measure | Time frame |
|---|---|
| MACE (recurrent angina, stent thrombosis, nonfatal myocardial infarction, stroke, cardiovascular death; | — |
Countries
China
Contacts
Public ContactZheng Ji
Tangshan Worker Hospital
Outcome results
None listed