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A prospective cohort study on diagnosis and treatment evaluation of infectious pneumonia through exhaled volatile organic compounds analyzation by a real-time high-pressure photon ionization time-of-flight mass spectrometry

A prospective cohort study on diagnosis and treatment evaluation of infectious pneumonia through exhaled volatile organic compounds analyzation by a real-time high-pressure photon ionization time-of-flight mass spectrometry

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000032733
Enrollment
Unknown
Registered
2020-05-08
Start date
2020-06-01
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectious pneumonia

Interventions

Gold Standard:Mycobacterium tuberculosis culture
volatile&#32
compounds.

Sponsors

Shenzhen Third People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 80 Years

Inclusion criteria

Inclusion criteria: In the third people's Hospital of Shenzhen, suspected cases of infectious pneumonia (including tuberculosis, viral pneumonia, bacterial pneumonia, fungal pneumonia) and healthy control group were included. TB suspected case standard: refer to WS 288-2017 TB diagnosis. For the suspected cases of viral pneumonia, bacterial pneumonia and fungal pneumonia, refer to the clinical diagnosis standards of community acquired pneumonia and hospital acquired pneumonia: refer to practical internal medicine (15th Edition).

Exclusion criteria

Exclusion criteria: 1. Severe pneumonia patients who can't get breath samples; 2. Karnofsky score < 50% (see Annex I); 3. According to the judgment of the subject group, the subject has any disease (such as serious mental illness, alcohol abuse, drug abuse or other related serious diseases affecting the treatment) that is not suitable for the subject or may prevent the patient from participating in the whole process of the subject.

Design outcomes

Primary

MeasureTime frame
Sensitivity of diagnosis of infectious pneumonia;Specificity of diagnosis of infectious pneumonia;Sensitivity of prediction of adverse drug reaction;Specificity of prediction of adverse drug reaction;Sensitivity of prediction of treatment outcome;Specificity of prediction of treatment outcome;

Countries

China

Contacts

Public ContactLiang Fu

Shenzhen Third People's Hospital

flk1981@qq.com+86 15989869571

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026