tuberculosis
Conditions
Interventions
Gold Standard:Diagnostic criteria for tuberculosis(WS288-2017)
Index test:lncRNA,mRNA,cirRNA
Sponsors
Beijing Chest Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria (1) Severe secondary tuberculosis group: Diagnose patients with secondary tuberculosis according to "Diagnostic Criteria for Tuberculosis (WS288-2008)". Mycobacterium tuberculosis sputum was positive for acid-fast staining. The lesion occupies >= 3 lung fields, with holes or serious complications. The newly treated patients did not receive anti-tuberculosis treatment. (2) Mild secondary tuberculosis group: patients with secondary tuberculosis diagnosed according to "Diagnostic Criteria for Tuberculosis (WS288-2008)". The selected case was active pulmonary tuberculosis, and mycobacterium tuberculosis sputum was positive for acid-fast staining. The lesion occupies <= 2 lung fields. The newly treated patients did not receive anti-tuberculosis treatment.
Exclusion criteria
Exclusion criteria: 1. Patients younger than 18 years old; 2. Patients with malignant tumors; 3. Patients with immune system diseases or receiving immunotherapy; 4. Patients infected with HIV, hepatitis B and hepatitis C virus; 5. Patients with complications during pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lncRNA;SEN, SPE, ACC, PPV, NPV, AUC of ROC; | — |
Secondary
| Measure | Time frame |
|---|---|
| mRNA;cirRNA; | — |
Countries
China
Contacts
Public ContactLiu Qiuyue
Beijing Chest Hospital Affiliated to Capital Medical University
Outcome results
None listed