Postoperative analgesia and complications of jaw tumor resection
Conditions
Interventions
Experimental group:Intravenous dexamethasone 0.2mg/kg 30 minutes before the end of operation
Control group:Intravenous normal salt solution 0.2mg/kg 30 minutes before the end of operation
Sponsors
Nantong University Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. To meet the criteria of diagnosis and treatment of benign tumor related diseases of maxilla and mandible in stomatology department; 2. Single benign tumor of jaw, and the maximum diameter of tumor <=5cm; 3. Patients aged 16-60 years old, weight 40-80kg, male and female unlimited; 4. The American Society of anesthesiologists (ASA) preoperative anesthesia grade I-II; 5. Patients and their families can understand and fill in various rating scales, and sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Patients with other related oral, maxillofacial or otorhinolaryngologic history and surgical treatment history; 2. Patients who have taken hormone drugs or opioid drugs for treatment; 3. Those with liver or kidney dysfunction, diabetes or heart dysfunction; 4. Patients with mental disorders, long-term history of taking analgesics, drug addiction and drug addiction; 5. Those who do not voluntarily cooperate with the patients or are judged by the researcher to be unsuitable for the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain;Facial swelling;Degree of mouth opening restriction; | — |
Secondary
| Measure | Time frame |
|---|---|
| CRP protein;Interleukin-6; | — |
Countries
China
Contacts
Public ContactZhu Xiang
Nantong University Affiliated Hospital
Outcome results
None listed