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Study on the relationship of EDNRA gene to large artery atherosclerotic stroke and the underlined mechanism

Study on the relationship of EDNRA gene to large artery atherosclerotic stroke and the underlined mechanism

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000032684
Enrollment
Unknown
Registered
2020-05-06
Start date
2020-06-01
Completion date
Unknown
Last updated
2020-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemic stroke

Interventions

LAS group:N/A
healthy control group:N/A

Sponsors

The Third People's Hospital of Chengdu
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
19 Years to 70 Years

Inclusion criteria

Inclusion criteria: The subjects were recruited from consecutive Han patients aged 19-70 years admitted with a first-ever IS. Inclusion criteria was as follows: (1) IS was defined according to the World Health Organization (WHO) Definition and confirmed by a brain computed tomography and/or magnetic resonance imaging scan showing a recent brain infarct corresponding to the clinical presentation within 2 weeks of the event; (2) only subjects with large artery atherosclerotic stroke; (3) the patients agreed to join.

Exclusion criteria

Exclusion criteria: The patients with IS secondary to other diseases and the LAA cases with liver /kidney disease, systemic infection, thrombolytic therapy, pregnancy, or other serious situation were excluded.

Design outcomes

Primary

MeasureTime frame
stroke onset;mRNA and protein expression of EDNRA, NLRP3 ;inflammatory cytokines;

Countries

China

Contacts

Public ContactLiu Hua

ment, the Third People's Hospital of Chengdu

hxliumedidoctor@163.com+86 18011351793

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026