Pancreatic cancer
Conditions
Interventions
Case series:Tiggio 40-60mg/d amlotinib 8mg/d
Sponsors
Cancer Hospital Affiliated to Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years old; 2. Patients with ECoG score =1.5x10^9/L; (2) Platelet >=80x10^9/L; (3) Hemoglobin >=80g/L; (4) Creatinine <=1.5 ULN; (5) Child liver function grade A or B.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to androtinib or tegio; 2. Patients with various factors affecting oral medication (including dysphagia, chronic diarrhea, intestinal obstruction, etc.); 3. Patients with abnormal coagulation (INR > 1.5, APTT > ULN); 4. Patients with severe heart disease include: (1) Angina pectoris; (2) Arrhythmias that need to be treated with drugs or have clinical significance (including significant abnormalities in baseline ECG, QTc interval > 450 ms in men and 470 MS in women); (3) Myocardial infarction; (4) Heart failure; (5) Left ventricular ejection fraction (LVEF) 140 mmHg, diastolic blood pressure > 90 mmHg) and patients with positive urine protein were also included; 6. Patients with other serious medical diseases, including cerebrovascular disease, uncontrolled infection, active peptic ulcer, etc; 7. Patients with central nervous system metastasis; 8. Pregnant and lactating women; 9. Patients who have been diagnosed with other tumors in the past 5 years; 10. Patients with mental illness or a history of psychoactive substance abuse; 11. The subjects that the researchers think should not participate in the experiment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OS; | — |
Countries
China
Contacts
Public ContactXiaoli Liao
Cancer Hospital Affiliated to Guangxi Medical University
Outcome results
None listed