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Multi-center, randomized, double-blind, controlled clinical efficacy observation of compound glycyrrhizin tablets in the treatment of childhood asthma and its regulation on Th17 / Treg signaling pathway

Multi-center, randomized, double-blind, controlled clinical efficacy observation of compound glycyrrhizin tablets in the treatment of childhood asthma and its regulation on Th17 / Treg signaling pathway

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032644
Enrollment
Unknown
Registered
2020-05-04
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childhood asthma

Interventions

experimental group:Compound Glycyrrhizin Tablets
control group:placebo

Sponsors

University of Chinese Acadaemy of Sciences Shenzhen Hosptial
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 14 Years

Inclusion criteria

Inclusion criteria: (1) Patients who meet the diagnostic criteria: the diagnostic and grading standards for bronchial asthma in the 8th edition of Zhufutang Practical Pediatrics; (2) Patients aged 3 - 14 years old; gender: male to female ratio 1: 1; (3) Condition: Moderate; (4) Those who voluntarily participated in this study, signed an informed consent, and agreed to abide by the treatment prescribed in this study.

Exclusion criteria

Exclusion criteria: (1) Combined with cardiopulmonary and other serious diseases and mental disorders; (2) Poor compliance and unable to cooperate with oral medication; (3) Those who have used drugs in the treatment group within 2 weeks before enrollment; (4) Those who are known to be allergic to the drugs and their ingredients used in this test; (5) Those who require oral or intravenous glucocorticosteroids due to their condition; (6) Those who are participating in other drug trials or have participated in other clinical trials within 4 weeks before enrollment.

Design outcomes

Primary

MeasureTime frame
Asthma control rate;Expression of Th17 cells in venous blood;Expression of Treg cells in venous blood;Blood;

Countries

China

Contacts

Public ContactJiahua Li

University of Chinese Acadaemy of Sciences Shenzhen Hosptial

1066068893@qq.com+86 15012719105

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026