Novel coronavirus pneumonia (COVID-19)
Conditions
Interventions
Sponsors
Hubei Provincial Hospital of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet the COVID-19 diagnostic criteria and discharge standards, but the later SARS-CoV-2 virus nucleic acid test is positive; (2) Aged 18 to 70 years old; (3) Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Accompanied by severe basic diseases affecting survival, including uncontrolled clinically significant heart, kidney, digestive, blood diseases, neuropsychiatric diseases, immune diseases, metabolic diseases, malignant tumors, severe malnutrition, etc.; 2. Unstable angina pectoris or myocardial infarction in the last 1 month; 3. Allergic constitution, allergic to the drug ingredients involved in the treatment program; 4. Pregnant or nursing women; 5. Mental state cannot cooperate, suffer from mental illness, have no self-control, cannot express clearly; 6. Participating in other clinical trials; 7. According to the judgment of the researchers, patients who will be included in the group will have complications or poor compliance, which will affect the efficacy and safety evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Qualitative RT-PCR results of SARS-CoV-2 nucleic acid of oral / nasopharyngeal swabs, anal swabs, sputum and blood ; | — |
Secondary
| Measure | Time frame |
|---|---|
| 2019-nCoV Antibody Test;Sars-cov-2 viral load levels in Oral / nasopharyngeal swab, anal swab, sputum, blood;Leukocyte, neutrophil, lymphocyte counts;lung CT;PBMC lymphocyte flow cytometry;Plasma cytokine assay;Detection and analysis of molecular immunogram;Detection of SARS-CoV-2 N and S proteins in pharyngeal swabs and saliva;Isolation and cultivation of SARS-CoV-2 virus;SARS-CoV-2 virus content in blood cell;Clinical symptoms by Visual analogue scale (VAS); | — |
Countries
China
Contacts
Public ContactHe Shaobin
Hubei Provincial Hospital of TCM
Outcome results
None listed