Papillary Thyroid Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Be diagnosed as papillary thyroid cancer (PTC) or suspected PTC by fine needle aspiration biopsy (Bethesda V or VI categories); 2. Intrathyroidal unifocal PTC, which surrounded by >=2 mm normal thyroid parenchyma; 3. Tumor size =18 years old; 7. Normal thyroid stimulating hormone level by electrochemiluminescence assay; 8. Patients had no psychological, family, social or geographical constraints that affected protocol adherence and follow-up; 9. Patients volunteering to participate and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with hashimotos disease or history; 2. Family history of thyroid cancer in immediate family member; 3. Previous cervical surgery history or other factors that may interfere with ultrasound examination (e.g. thyroiditis, lymphadenopathy, or, multifocal benign nodules); 4. With severe disease of cardiopulmonary, central nervous system disease, or other malignant tumor; 5. Mental disorder and cognition impairment that cannot correctly describe their feelings; 6. A history of alcohol, drug or substance abuse; 7. Expected duration of surveillance <3 months; 8. Patients or major family members who are unwilling to accept active surveillance protocol or have severe anxiety 9. For any other reason judged by the researcher as not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative rate of disease progression-free;Disease-specific survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| The quality of life score;Hamilton anxiety score; | — |
Countries
China
Contacts
The First Affiliated Hospital of Kunming Medical University