Parkinson's disease
Conditions
Interventions
Gold Standard:clinical outcome meet 2015 MDS-probable PD criteria
and 
analysis 
device,Wearable 
Sponsors
Shanghai Jiao Tong University School of Medicine affiliated Shanghai General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Male or female aged 50 years or older at time of PD diagnosisA diagnosis of Parkinson disease for 1 year or moreSubjects must have at least two of the following: resting tremor, bradykinesia, rigidity (must have either resting tremor or bradykinesia as one of two symptoms); OR either asymmetric resting tremor or asymmetric bradykinesia. Dopamine treatment effectiveModified Hoehn and Yahr stage IIV at screening, Able to give written informed consent, as determined by the investigator. Able to perform all study activities (including walking tasks and timed up and go), Willingness and ability to comply with study requirements.
Exclusion criteria
Exclusion criteria: A diagnosis of atypical parkinsonism, drug-induced parkinsonism, essential tremor, primary dystonia or other diagnoses that explain symptoms other than PD. A diagnosis of a significant CNS disease other than PD; history of repeated head injury; history of epilepsy or seizure disorder other than febrile seizures as a child that would interfere with ability to perform study assessments. History of a brain magnetic resonance imaging (MRI/CT) scan indicative of clinically significant abnormality as determined by the investigator. Concomitant disease, condition, medication, or laboratory abnormality that, in the opinion of the investigator, could interfere with study conduct or analysis, or pose an unacceptable risk to the participant. This could include neurologic, orthopedic or cardiovascular diseases. Drug abuse, excessive drinking or malnutrition. Nose, mouth or throat disease influence voice quality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive impairment;Fall risk; | — |
Countries
China
Contacts
Public ContactLiu Ye
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine,
Outcome results
None listed