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Clinical Randomized Controlled Trial for Repeated Transcranial Magnetic Stimulation on Sleep Disorder in Children with Autism Spectrum Disorder

Clinical Randomized Controlled Trial for Repeated Transcranial Magnetic Stimulation on Sleep Disorder in Children with Autism Spectrum Disorder

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032605
Enrollment
Unknown
Registered
2020-05-03
Start date
2020-06-01
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep Disorder in Children with Autism Spectrum Disorder

Interventions

control group: Sleep Behavior Education and Treatment

Sponsors

Guangzhou Women and Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. The children must also comply with the fifth edition (The fifth edition of The Diagnostic and Statistical Manual of Mental Disorders,DSM-5) of the Diagnostic and Statistical Manual for Mental Disorders issued by the American Psychiatric Association in 2013 and the third edition (International Classification Sleep Disorder-3,ICS) of the 2014 International Classification of Sleep Disorders D-3) Diagnostic criteria for sleep disorders. 2. Aged 3-6 years, gender unlimited. 3. Difficult to fall asleep, impedance to bed, frequent or prolonged night waking, excessive early waking, restless sleep, day and night rhythm disorder, sleepwalking, night terrors, short sleep duration, nocturnal enuresis, daytime sleepiness, sleep apnea disorder, habit of late sleeping typical clinical symptoms. 4. No antipsychotic, sedative and hypnotic drugs were taken within 4 months. 5. The guardian volunteered the child to participate in the study and was able to cooperate with the study and signed the informed consent for the study.

Exclusion criteria

Exclusion criteria: 1. The nervous system has organic lesions, such as: brain softening, white matter dysplasia, brain dysplasia and so on. 2. The common ASD, of neurodevelopmental disorders with definite etiology are: ret syndrome, disintegrating mental disorders in children, angel syndrome, brittle X syndrome, tuberous sclerosis, etc. 3. Organic diseases of the circulatory system; respiratory diseases such as sleep-related respiratory disorders caused by abnormal anatomical structures (e.g. airway stenosis), local tissue compliance and neurophysiological causes; and those suffering from acute diseases affecting sleep in the last week. 4. Epilepsy. 5. rTMS related contraindications, such as the skull built-in metal foreign body, cochlear implants, intracranial pressure significantly increased, and so on. 6. ASD children whose parents are considered unable to carry out a sleep behaviour treatment plan (e.g. parents are unable to carry out the plan due to frequent absence from work during the intervention or family problems with serious interference).

Design outcomes

Primary

MeasureTime frame
Children's Sleep Habits Questionnaire;Household Sleep Habits Survey;Child Behavior Scale;Pineal gland volume;

Countries

china

Contacts

Public ContactXU Kaishou

Guangzhou Women and Children's Medical Center

xksyi@126.com+86 13422250582

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026