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Study for the Role of Long non-coding RNA C008080.1 and P53 Gene in Preserving Fertility of Cervical Tumors

Study for the Role of Long non-coding RNA C008080.1 and P53 Gene in Preserving Fertility of Cervical Tumors

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000032592
Enrollment
Unknown
Registered
2020-05-03
Start date
2020-05-20
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Tumor

Interventions

Sponsors

Maternal and Child Health Hospital of Huai'an City, Jiangsu Province
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) The collection of clinical tissue specimens is subject to the patient's informed consent and approved by the hospital ethics committee. All patients requiring surgical resection of the uterus, cervix or cervical biopsy are tested for HPV before surgery. All specimens were diagnosed by routine pathological examination. At the same time, a small amount of fresh tissue was taken from each specimen, washed with physiological saline, and transferred to a -70 oC refrigerator for storage. (2) Specimens are divided into 4 groups: CC group, HSIL group, LSIL group, and non-neoplastic cervical group. Inclusion criteria of each group of specimens: cervical tissue specimens of CC group, HSIL group, and LSIL group must be HPV16 positive, and non-tumor cervical tissue specimens must be HPV negative. Number of specimens included: 50 cases each in CC group, HSIL group, LSIL group and non-neoplastic cervical group.

Exclusion criteria

Exclusion criteria: Cervical tissue specimens of CC group, HSIL group and LSIL group must be HPV16 negative.

Design outcomes

Primary

MeasureTime frame
C008080.1-201;p53;

Countries

China

Contacts

Public ContactYANG HUI

Maternal and Child Health Hospital of Huai'an City, Jiangsu Province

ppoouu@126.com+86 13915150279

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026