Cervical Tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The collection of clinical tissue specimens is subject to the patient's informed consent and approved by the hospital ethics committee. All patients requiring surgical resection of the uterus, cervix or cervical biopsy are tested for HPV before surgery. All specimens were diagnosed by routine pathological examination. At the same time, a small amount of fresh tissue was taken from each specimen, washed with physiological saline, and transferred to a -70 oC refrigerator for storage. (2) Specimens are divided into 4 groups: CC group, HSIL group, LSIL group, and non-neoplastic cervical group. Inclusion criteria of each group of specimens: cervical tissue specimens of CC group, HSIL group, and LSIL group must be HPV16 positive, and non-tumor cervical tissue specimens must be HPV negative. Number of specimens included: 50 cases each in CC group, HSIL group, LSIL group and non-neoplastic cervical group.
Exclusion criteria
Exclusion criteria: Cervical tissue specimens of CC group, HSIL group and LSIL group must be HPV16 negative.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C008080.1-201;p53; | — |
Countries
China
Contacts
Maternal and Child Health Hospital of Huai'an City, Jiangsu Province