Effect of dexamethasone on postoperative pain after cesarean section

Dexamethasone alleviates acute inflammatory pain by inhibiting neurons in DRG and relieves chronic inflammatory pain by inhibiting the activation of microglia

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000032589

Enrollment

Unknown

Registered

2020-05-03

Start date

2020-05-04

Completion date

Unknown

Last updated

2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia

Interventions

experience group:Dexamethasone in postoperative analgesia pump

Control group:Sufentanil and Dexamethasone in postoperative analgesia pump

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. The first cesarean section subjects, 37-41 weeks gestation, single pregnancy; 2. Patients aged 18-35, ASA I-II; 3. Patients who did not take opioid analgesics during pregnancy; 4. Patients without contraindications to cesarean section.

Exclusion criteria

Exclusion criteria: 1. Patients with pregnancy complications such as diabetes mellitus, pregnancy induced hypertension and placental abruption; 2. Patients with liver and kidney dysfunction or coagulation dysfunction; 3. Patients with opioid allergy or dependence; 4. Patients with mental disorders and a long history of taking analgesics; 5. Patients with drug addiction and drug use history.

Design outcomes

Primary

Measure	Time frame
VAS score of knife edge pain;	—

Secondary

Measure	Time frame
Press times of analgesia pump;Total dose of drugs by pressing analgesia pump;	—

Countries

China

Contacts

Public ContactZhou Wang

Nantong University

137747161@qq.com+86 15251308939

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026