lower abdominal cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-60 years who underwent selective surgery for tumors of the lower abdomen (colorectal cancer, urological tumor, gynecological tumor); 2. ASA level I-III; 3. Patients who use electronic controlled intravenous analgesia pump for postoperative analgesia, and the analgesic pump contains butorphanol tartrate; 4. Patients who used butorphanol tartrate for analgesia and sedation in perioperative period; 5. The patient or family member has signed the informed consent;
Exclusion criteria
Exclusion criteria: 1. Patients with opioid tolerance; 2. Patients who depend on nacodine; 3. Pregnant and lactating women; 4. Patients with mental illness or other reasons unable to cooperate; 5. Patients with central nervous system disease, craniocerebral injury or intracranial pressure rise before operation; 6. Patients with a history of chronic pain, long-term use of sedatives and antidepressants before operation; alcoholism; 7. Patients who take CNS stimulants or suffer from CNS disease or respiratory dysfunction at the same time; 8. Patients with myocardial infarction, ventricular dysfunction and coronary insufficiency; 9. Patients who participated in clinical studies of other drugs in recent three months; 10. The scope of operation involves diaphragm operation (reduction of ovarian cancer); 11. Patients with creatinine clearance rate < 80ml / min; 12. Patients younger than 18 years old.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain score;Ramsay Sedation score;Clavien Dindo grading system e;Recovery quality rating scale; | — |
Countries
China
Contacts
Fudan University Shanghai Cancer Center