Hyoxemia
Conditions
Interventions
Intravenous anesthesia group 2: Laryngeal Mask Airway
Intravenous anesthesia group 1:New endoscopic nasal mask
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1)The age 18-70 years old; (2) Urological surgery or gynecologic surgery (urology: bladder calculi; Gynecology: hysteroscopy) of the patient; (3) 18Kg/m2 <= BMI <= 28Kg/m2; (4) ASA(American society of anesthesiologists) I-III; (5) Able to understand the research process and communicate effectively with researchers; (6) Volunteer to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Abnormal liver function (ALT or AST > 2 x ULNor TBIL >= 1.5 x ULN); (2) Renal injury(serum creatinine > 112µmol/L), or received dialysis treatment within 28 days before surgery; (3) Patients with active upper respiratory tract infection or pneumonia; (4) During the screening period, the resting electrocardiogram of the patient was obviously abnormal, and the researcher determined that the patient was not suitable for the test; (5) Antihypertensive drugs were used to treat hypertensive patients whose blood pressure was not satisfactorily controlled (Sitting systolic pressure during screening >= 160mmHg; and/or Diastolic blood pressure screening period >= 105mmHg); (6) Diabetic patients with unsatisfactory control of blood glucose (Fasting blood glucose during screening >= 11mmol/L); (7) Patients at high blood risk, including those taking anticoagulant and antiplatelet drugs, Patients with congenital haemorrhagic diseases (e.g. hemophilia), thrombocytopenia(PLT < 50 x10^9/L). Patients with platelet dysfunction (e.g. idiopathic thrombocytopenic purpura diffuse intravascular coagulation congenital platelet dysfunction) or patients with clinically significant bleeding under any activity; (8) Patients with neck injuries who are at risk for neck instability (such as rheumatoid arthritis or down's syndrome) or who have reduced neck range of motion, limited mouth opening, oropharyngeal structural abnormalities, and vertebral artery occlusion; (9) Participated in other clinical trials in 30 days; (10) Patients with existing sore throat; (11) Patients with chronic respiratory disease or hyperreactive airway disease; (12) Patients with underlying airway obstruction (e.g., obstructive sleep apnea, abnormal tonsil enlargement, airway compression, tracheomalacia, pharyngeal tumor, abscess, hematoma, etc.); (13) Patients with satiety, increased abdominal pressure, tendency of vomiting reflux aspiration (such as obesity, hiatal hernia, pregnancy, autonomic nerve dysfunction), inertia vomiting patients; (14) Surgery has strict muscle relaxation requirements in patients; (15) The expected operation time is more than 1 hour; (16) Other reasons why the researchers considered it inappropriate to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of hypoxemia;pulse oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| pharyngalgia;laryngospasmus;Reflux aspiration;pulmonary edema; | — |
Countries
China
Contacts
Public ContactYu Bin
Shanghai Tongji Hospital
Outcome results
None listed