The carbon dioxide absorption capacity of soda lime (Sofnolime2550WV) in low-flow closed-circuit general anesthesia.

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000032554

Enrollment

Unknown

Registered

2020-05-02

Start date

2020-05-01

Completion date

Unknown

Last updated

2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing brain surgery under general anesthesia

Interventions

Group 0ne:PiCO2=1mmHg

Group Two:PiCO2=3mmHg

Group Three:PiCO2=5mmHg

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged from 18 to 70 years; 2. Selective operation of the brain patients undergoing low-flow general anesthesia; 3. PiCO2 in the mindray monitor > 0.

Exclusion criteria

Exclusion criteria: 1. Patients suffered from lung diseases included pulmonary tuberculosis, pulmonary infection, COPD, pulmonary edema, Emphysema and asthma; 2. Patients suffered from high intracranial pressure, hypertension, pulmonary hypertension and heart disease can not tolerate hypercapnia.

Design outcomes

Primary

Measure	Time frame
PetCO2;PaCO2;	—

Secondary

Measure	Time frame
BP and HR;BE;	—

Countries

China

Contacts

Public ContactQiulan He

Department of Anesthesiology, the First Affiliated Hospital Sun Yat-Sen University

evelyn0809@126.com+86 13570495107

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026