calcium oxalate urinary stone
Conditions
Interventions
Drug combination group:Combined with oxalic acid degrading enzyme and vitamin B6, vitamin E
Oxalic acid degrading enzyme treatment group:Take oxalate degrading enzyme
Vitamin treatment group:Take vitamins
Sponsors
Department of Urology, Wuming Hospital Affiliated to Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients who agree to participate in this clinical trial and sign informed consent. 2. Age: 18-75, regardless of gender. 3. Patients with double J tube after urolithiasis surgery. 4. The stone composition was determined by the infrared spectrum automatic analyzer to be calcium oxalate stone (or mixed stone with calcium oxalate stone as the main component). 5. Good medication compliance and long term follow-up. 6. Patients who have not taken corresponding drugs to prevent recurrence of calcium oxalate stones after calculus surgery.
Exclusion criteria
Exclusion criteria: 1. Severe abnormalities of liver or renal function, middle or severe hydroureteral hydronephrosis, or ureteral stricture; 2. Patients with uncontrolled systemic diseases and severe urinary tract infection and infectious stones; 3. Severe renal diseases (glomerulonephritis, renal failure, renal tumor); 4. Patients with intolerance to oral vitamin E, B6 and oxalic acid degrading enzyme; 5. Pregnant or nursing women; 6. Patients with other serious diseases who are likely to die during treatment and follow-up; 7. Other ineligible patients as determined by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of calcium oxalate crystals in urine;DJ tube weight gain; | — |
Countries
china
Contacts
Public ContactTang Yong
Department of Urology, Wuming Hospital Affiliated to Guangxi Medical University
Outcome results
None listed