Skip to content

Study on the protective effect of hydrogen on patients with subarachnoid hemorrhage

Effect of continuous hydrogen inhalation therapy on early brain injury in patients with subarachnoid hemorrhage

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032529
Enrollment
Unknown
Registered
2020-05-01
Start date
2020-09-01
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subarachnoid hemorrhage

Interventions

Intervention group:Hydrogen inhalation

Sponsors

Department of Neurosurgery, Gulou Hospital Affiliated to Medical College of Nanjing University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients or entrusted family members voluntarily sign the informed consent of the test; 2. Patients aged 20 years or older and 70 years or younger, regardless of gender, with aneurysmal SAH; 3. In SAH patients with ruptured aneurysm, hunt Hess score was 3 or 4; 4. Patients who completed interventional therapy within 72 hours after aneurysm rupture.

Exclusion criteria

Exclusion criteria: 1. Patients who are judged by the responsible physician to be unsuitable for the trial; 2. Severe brain edema, cardiac insufficiency and renal insufficiency; 3. Patients with large amount of intracranial hematoma or hydrocephalus; 4. Those who refused to randomize; 5. Patients who could not be enrolled for any reason, according to the researchers.

Design outcomes

Primary

MeasureTime frame
Brain edema;Vasospasm;Inflammatory factors;

Secondary

MeasureTime frame
Glasgow Coma Scale;WFNS grading system;Hunt-Hess scale;Glasgow outcome scale;

Countries

China

Contacts

Public ContactZhuang Zong

Gulou Hospital Affiliated to Medical College of Nanjing University

zhuangzong@126.com+86 15850560410

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026