Benign Prostatic Hyperplasia
Conditions
Interventions
Precise Anatomic Enucleation:HoLEP
Sponsors
Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University
Eligibility
Sex/Gender
Male
Age
50 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Sign informed consent; 2. Chinese male aged 50-100 (including 50 years old, 100 years old); 3. Meet the western medical diagnostic criteria for benign prostatic hyperplasia; 2) IPSS >= 12 points; 3) prostate volume> 25 cm3; 4) maximum urine flow rate (Qmax) <15 ml / s; 5) PSA <= 4ng / ml or clinical Exclude prostate cancer. 5) Alpha receptor blocker (one of naftopidil, terazosin, afurazosin, tamsulosin, tamsulosin) and 5a reductase inhibition after at least 6 months before surgery Combination (finasteride). 4. Preoperative examination results must be completed within 30 days before enrollment.
Exclusion criteria
Exclusion criteria: 1. Illnesses or conditions that affect patients' understanding, following and / or following the research process; 2. One of the following conditions was confirmed before surgery: 1) neurogenic bladder dysfunction; 2) history of lower urinary tract injury or previous prostate or urethral surgery; 3) known bladder tumor; 4) known urethral stricture or Bladder neck contracture; 5) Combined with other advanced malignancies; 3. Contraindications to other operations and anesthesia; 4. Other circumstances that the researcher considers inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Qmax;IPSS;QoL; | — |
Secondary
| Measure | Time frame |
|---|---|
| Volume of postoperative flushing fluid;Complications; | — |
Countries
China
Contacts
Public ContactZhong Wang
Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University
Outcome results
None listed