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A randomized, controlled, study for evaluating the efficacy of corticosteroid injection/home-based exercise intervention in the treatment of meniscal tear with knee osteoarthritis

The efficacy of exercise intervention in patients with knee osteoarthritis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032508
Enrollment
Unknown
Registered
2020-04-30
Start date
2020-06-01
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

meniscal tear with knee osteoarthritis

Interventions

Intervention group:Home-based exercise
Controlled goup:corticosteroid injection

Sponsors

Sports Science Research Institute of Hebei Province
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Meet Altmans clinical criteria for knee osteoarthritis; 2. Have radiographic evidence of knee osteoarthritis (Kellgren-Lawrence radiographic scale class 2-3); 3. Aged 18-60 years; 4. Symptoms consistent with torn meniscus (at least one of the following: clicking, catching, popping, giving way, pain with pivot or torque, pain that is episodic, pain that is acute and localized to one joint line); 5. Evidence on knee MRI of osteophytes or full-thickness cartilage defect; or plain radiographic evidence of osteophytes or joint space narrowing; 6. Evidence on knee MRI of a meniscal tear that extends to the surface of the meniscus; 7. Aable to give informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Steroid injections or physical therapy treatment for their knee in the past 12 months; 2. Current or past history of rheumatoid arthritis or similar rheumatic condition; 3. Current or past history of gout or pseudogout of the knee; 4. Active infection in the knee within the past 12 months; 5. Typically more limiting or painful than their knee osteoarthritis during activities included sitting, standing, walking, or stair climbing; 6. History of allergy or adverse effect to corticosteroids; 7. Pregnant or intending to become pregnant; 8. Contraindication to receiving a corticosteroid injections (history of allergic or adverse reaction to steroids or steroid injection, history of multiple corticosteroid injections in that area even if not within last year, uncontrolled diabetes mellitus, etc.); 9. Previous received TKA or UKA surgery; 10. Other reasons for exclusion (Severe organ failure, specifically patients with cardiovascular diseases, classified as New York Heart Association class III or IV, chronic kidney disease classified as stage >= 3, liver disease with a Model of End-stage Liver Disease score of >= 20, and patients with severe mental illness, lack of permanent home address, drug abuse, alcohol abuse).

Design outcomes

Primary

MeasureTime frame
WOMAC;VAS;

Secondary

MeasureTime frame
SF-36;Alternate Step Test;Timed Up and Go test;

Countries

China

Contacts

Public ContactJing Yanzhong

Sports Science Research Institute of Hebei Province

jingxiaochao1995@gamil.com+86 13303111233

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026