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The study on the correlation between anesthesia depth and postoperative cognitive dysfunction

The study on the correlation between anesthesia depth and postoperative cognitive dysfunction

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032463
Enrollment
Unknown
Registered
2020-04-29
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative cognitive dysfunction

Interventions

Group 1:Use the anesthesia depth monitor (bispectral index)
Group 2:without the anesthesia depth monitor (bispectral)

Sponsors

The Second People's Hospital of Yibin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients who are intended to undergo laparoscopic gastrointestinal elective surgery under the total intravenous anesthesia in The Second People's Hospital of Yibin. 2. The surgery take more than 120 minutes. 3. More than 18 years old. 4. ASA grade I-III.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of mental and neurological diseases, a long history of alcohol and drug abuse, and long-term use of opioids or antipsychotic drugs. 2. Patients with severe heart, lung, brain, liver and kidney dysfunction, with a history of diabetes and stroke. 3. The mini-mental State Examination (MMSE) confirmed the existence of cognitive dysfunction, and the score of MMSE was less than 20 points.(due to China's national conditions, the enrolled patients are generally older and have a low level of education, so 20 points are adopted as the threshold.) 4. Patients who are deaf and blind cannot complete the test 5. Patients who refuse the test or cannot complete the test due to other reasons. 6. Allergy to anesthetic drugs that need to be applied during the experiment, and patients with a family history of malignant hyperthermia or a history of malignant hyperthermia.

Design outcomes

Primary

MeasureTime frame
postoperative cognitive dysfunction;Postoperative delirium;

Countries

China

Contacts

Public ContactGuangyun Sun
33197132@qq.com+86 13990961909

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026