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Effect of yogurt milk on patients with polycystic ovary syndrome

Effect of yogurt milk on microbiome structure and reproductive health in patients with polycystic ovary syndrome

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032454
Enrollment
Unknown
Registered
2020-04-28
Start date
2020-04-29
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

control group:Drinking 166 yogurt
PCOS group 1:Drinking 166 yogurt
PCOS group 2:common milk
PCOS group 3:conventional hormone therapy
PCOS group 4:conventional hormone therapy and 166 yogurt

Sponsors

Beijing Sanyuan Food Co., Ltd.
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: PCOS was diagnosed after other causes of anderothhormoneemia and/or ovulation dysfunction (Cushing syndrome, 21-hydroxylase deficiency, thyroid disease, androgen secretion tumors, congenital adrenal hyperplasia and hyperlactinemia). Diagnostic criteria for PCOS: According to the Rotterdam 2003 standard, at least two of the following criteria are met: (1) thin ovulation/no ovulation; (2) clinical manifestations of androthal hormones and/or hyperpositive hormone biochemical indicators; (3) ovarian polycystic changes: ultrasound suggests that one or both ovaries have a diameter of more than 2 to 12 9mm follicle, and/or ovary volume of 10 ml. All PCOS patients were first-time patients and did not receive PCOS-related treatment.The control group came from women who chose to do IVF for normal menstrual cycle, ovarian morphology and hormone water due to her husband's sperm problems.

Exclusion criteria

Exclusion criteria: Exclude women who have been breastfed or pregnant in the past year or who have taken medication in the past 3 months. Those who took antibiotics, probiotics or probiotics in the last 1 month, smoking regularly, drinking alcohol, and mental illness estonic diseases were not included in the study.

Design outcomes

Primary

MeasureTime frame
Stool microbial structure;Microbial structure of urine;Microbial structure of vaginal secretions;Saliva microbial structure;Metabolic components of stools;Metabolic composition of plasma;The microbiotic structure of blood;

Countries

China

Contacts

Public ContactChen Lijun
chenlijun@sanyuan.com.cn+86 18001388576

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026