Rosacea
Conditions
Interventions
experimental group:Taking the experimental drug
Sponsors
Department of Dermatology, Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: After 12 weeks of routine oral doxicycline and other drug treatment, patients with or without other treatment methods (topical drug /IPL and other treatment), treatment resistance (erythema stage did not decline by 1 grade or erythema greater than or equal to 3 degrees), or patients with frequent relapse during 12 weeks of treatment.
Exclusion criteria
Exclusion criteria: Subjects who met one of the following conditions were excluded from the study: 1. Aged 65 years; 2. Pregnant and lactating women and those who have a recent pregnancy plan; 3. Patients with moderate or severe systemic diseases including liver, kidney, lung or blood; Patients with bleeding tendency and acute and chronic gastrointestinal ulcer; 4. Patients with rosacea associated with Phymatous nose; 5. Oral administration of vitamin A acid within 3 months, oral administration of glucocorticoids or antibiotics within 1 month; 6. Treatment with glucocorticoid ointment or tacrolimus (pimeimus) or laser within 1 month; 7. The appearance of the face with other facial skin diseases or other diseases; 8. Patients who are not expected to follow up; 9. Have participated in any clinical trial within one month; 10. Mental disorder; 11. People who are allergic to aspirin or other salicylate, tetracycline or any other component of the drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the degree of improvement of rosacea score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of clinical symptom severity of rosacea;VISIA photos of rosacea patients;the quality of life;General view of the facial skin of rosacea patient; | — |
Countries
China
Contacts
Public ContactJi Li
Department of Dermatology, Xiangya Hospital, Central South University
Outcome results
None listed